Editorial Volume 10, Issue 9 pp 2222—2223

Molecular ultrasound imaging of JAM-A depicts early arterial inflammation

Figure 1. Scheme illustrating molecular ultrasound imaging with targeted, fluorescent, polymeric ultrasound microbubbles. While ICAM-1 served as a general target of vascular inflammation, VCAM-1 and αvβ3 faithfully enabled the assessment of major damages of the vascular wall and its regeneration. JAM-A particularly qualified as a very early marker of endothelial activation being translocated to the endothelial surface under altered vascular flow (Clip art was used from the Servier’s “Medical Art” database (http://www.servier.com/Powerpoint-image-bank) and modified).