Research Paper Volume 10, Issue 10 pp 2570—2584

CLCA4 inhibits cell proliferation and invasion of hepatocellular carcinoma by suppressing epithelial-mesenchymal transition via PI3K/AKT signaling

Figure 1. The expression of CLCA4 was downregulated in hepatocellular carcinoma tissues. (A) Immunohistochemistry assays of CLCA4 expression in HCC samples and adjacent non-tumorous tissues. The upper left panel represents high CLCA4 expression in adjacent non-tumorous tissues. The upper middle and right panel represents low and high CLCA4 expression in HCC tissues. Lower panels represent magnified pictures of boxed area in the corresponding upper panels. The line scale bar represents 50 μm. (B) CLCA4 expression in HCC tissues was compared with that in adjacent non-tumorous samples. Statistical analysis was performed by Paired-Samples t-test.