CLCA4 inhibits cell proliferation and invasion of hepatocellular carcinoma by suppressing epithelial-mesenchymal transition via PI3K/AKT signaling

Zhao Liu; Mi Chen; Lin-Ka Xie; Ting Liu; Zhen-Wei Zou; Yong Li; Peng Chen; Xin Peng; Charlie Ma; Wen-Jie Zhang; Pin-Dong Li

doi:doi:10.18632/aging.101571

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Research Paper Volume 10, Issue 10 pp 2570—2584

CLCA4 inhibits cell proliferation and invasion of hepatocellular carcinoma by suppressing epithelial-mesenchymal transition via PI3K/AKT signaling

Figure 3. Combined value of CLCA4 and serum AFP identify different risks of HCC death and recurrence. The associations of CLCA4/AFP co-expression with Overall survival (log-rank P < 0.001) (A) and Time to recurrence (log-rank P < 0.001) (B) in 186 HCC patients.