Research Paper Volume 10, Issue 10 pp 2695—2708

Role of alternative splicing of VEGF-A in the development of atherosclerosis

Figure 1. AS is induced HFD-treated ApoE (-/-) mice. ApoE (-/-) mice were fed with High-fat diet (HFD; simplified as HFD mice) for 12 weeks to induce experimental AS. The littermate ApoE (-/-) mice that had received normal diet (NOR) were used as a control. (A) Plaque area. (B) Circumferential plaque extension. (C) Maximal plaque thickness. *p<0.05. N=10.