Research Paper Volume 10, Issue 10 pp 2772—2782

Autophagy of macrophages is regulated by PI3k/Akt/mTOR signalling in the development of diabetic encephalopathy

Figure 5. Macrophage autophagy is salvaged by RAP and further suppressed by CQ in STZ-treated rat brain. The rat brain was dissociated into single cells to sort CD68+ macrophages. (A) Representative flow charts. (B) Western blot for LC3 and quantification LC3-II/I ratio. *p<0.05. N=10.