Research Paper Volume 10, Issue 10 pp 2991—3004

Sirt1/Nrf2 pathway is involved in oocyte aging by regulating Cyclin B1

Figure 7. The correlation between Nrf2 and age in granular cells. (A) The relative mRNA levels of Nrf2 were determined by RT-qPCR in control and old granular cells. mRNA levels in control granular cells were set to 1. Data are expressed as the mean ± SD. (B) The relative mRNA level of Nrf2 was determined by RT-qPCR in young (22-35 years) and old (36-49 years) ovarian granular cells. Data are expressed as the mean ± SD, *P<0.05 vs. young group. (C) Analysis of correlation between Nrf2 expression and age in human ovarian granular cells. R=-0.5972.