Research Paper Volume 10, Issue 12 pp 3683—3701

A functional variant of SMAD4 enhances macrophage recruitment and inflammatory response via TGF-β signal activation in Thoracic aortic aneurysm and dissection

Figure 6. The construction of TAA animal model. (A) The flow diagram of modeling process for TAA mouse in Wild Type and SMAD4 KD group; (B) The schematic diagram for generation of SMAD4 KD mice; (C) The DNA electrophoretogram of identification for Wild Type mice and SMAD4 KD mice.