Research Paper Volume 10, Issue 12 pp 3683—3701

A functional variant of SMAD4 enhances macrophage recruitment and inflammatory response via TGF-β signal activation in Thoracic aortic aneurysm and dissection

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Figure 6. The construction of TAA animal model. (A) The flow diagram of modeling process for TAA mouse in Wild Type and SMAD4 KD group; (B) The schematic diagram for generation of SMAD4 KD mice; (C) The DNA electrophoretogram of identification for Wild Type mice and SMAD4 KD mice.