Research Paper Volume 10, Issue 12 pp 3702—3712

BCAR4 activates GLI2 signaling in prostate cancer to contribute to castration resistance

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Figure 1. BCAR4 is upregulated in CRPC and correlated with poor prognosis of patients. (A) BCAR4 levels were examined in 50 pairs of castration-sensitive prostate cancer (CSPC) and paired adjacent normal prostate tissues (NT), by RT-qPCR. (B) 50 CSPC and 40 CRPC specimens were assessed by BCAR4 by RT-qPCR. (C) The 40 CRPC tissues were classified into two groups using the median value of all cases as the cutoff point. The Kaplan-Meier curves was used to analyze patients’ overall survival.