Research Paper Volume 10, Issue 12 pp 3702—3712

BCAR4 activates GLI2 signaling in prostate cancer to contribute to castration resistance

Figure 1. BCAR4 is upregulated in CRPC and correlated with poor prognosis of patients. (A) BCAR4 levels were examined in 50 pairs of castration-sensitive prostate cancer (CSPC) and paired adjacent normal prostate tissues (NT), by RT-qPCR. (B) 50 CSPC and 40 CRPC specimens were assessed by BCAR4 by RT-qPCR. (C) The 40 CRPC tissues were classified into two groups using the median value of all cases as the cutoff point. The Kaplan-Meier curves was used to analyze patients’ overall survival.