Research Paper Volume 10, Issue 12 pp 3806—3820

Circular RNA EIF6 (Hsa_circ_0060060) sponges miR-144-3p to promote the cisplatin-resistance of human thyroid carcinoma cells by autophagy regulation

Figure 3. CircEIF6 and miR-144-3p had a target relationship and a reversed expressed in the TPC1 and BHT101 cells with cisplatin treatment. (A) There are potential 2 target binding sites between miR-144-3p and circEIF6. (B) Expressions of circEIF6 were detected in the TPC1 and BHT101 cells with different time cisplatin treatment. *P < 0.05 compared with 0 h. C. The miR-144-3p expressions were detected in the TPC1 and BHT101 cells without or with cisplatin treatment. *P < 0.05 compared with control group. D. The circEIF6 probe successfully increased the circEIF6 and miR-144-3p expressions in TPC1 and BHT101 cells with cisplatin treatment. *P < 0.05 compared with probe-control group.