Research Paper Volume 10, Issue 12 pp 3957—3985

Integrated multi-omics characterization reveals a distinctive metabolic signature and the role of NDUFA4L2 in promoting angiogenesis, chemoresistance, and mitochondrial dysfunction in clear cell renal cell carcinoma

Figure 3. Schematic model summarizing the differences in tricarboxylic acid (TCA) cycle metabolites between normal and tumor tissue (A). Alterations in amino acid and lipid metabolism (B).