Research Paper Volume 10, Issue 12 pp 3957—3985

Integrated multi-omics characterization reveals a distinctive metabolic signature and the role of NDUFA4L2 in promoting angiogenesis, chemoresistance, and mitochondrial dysfunction in clear cell renal cell carcinoma

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Figure 3. Schematic model summarizing the differences in tricarboxylic acid (TCA) cycle metabolites between normal and tumor tissue (A). Alterations in amino acid and lipid metabolism (B).