Research Paper Volume 10, Issue 12 pp 3986—3999

Injury factors alter miRNAs profiles of exosomes derived from islets and circulation

Figure 4. Validation of exosomal miRNAs detected by microarray. Four miRNAs with top high FC values (FC>1.5 in both STZ and cytokines treated groups) miR-375-3p (A), miR-129-5p (B), miR-378a-3p (C), miR-382-5p (D) were further verified by qRT-PCR in three independent samples. The data are presented as mean±SEM. (* P<0.05, ** P<0.01 compared with control).