Research Paper Volume 10, Issue 12 pp 4120—4140

Overexpression of FoxM1 predicts poor prognosis of intrahepatic cholangiocarcinoma

Figure 1. FoxM1 was upregulation in ICC and correlated with survival. The mRNA expression (A) and protein expression (B) of FoxM1 in ICC tumor tissues compared with the expression in paired peritumoral tissues. (C) Representative immunohistochemical staining images of FoxM1 in ICC. (D) The bar graph shows the statistics for the staining intensity of FoxM1 in 184 ICC tumor samples and paired peritumoral tissues. (E) Kaplan-Meier curves for the overall survival and disease-free survival of 184 patients with ICC according to the expression of FoxM1. Abbreviations: ICC, intrahepatic cholangiocarcinoma; P, peritumoral tissue; T, tumor tissue. *P < 0.05.