Research Paper Volume 10, Issue 12 pp 4152—4165

Mechanistic insight into hyaluronic acid and platelet-rich plasma-mediated anti-inflammatory and anti-apoptotic activities in osteoarthritic mice

Figure 2. Effects of HA+PRP on inhibition of cellular apoptosis-related proteins in chondrocytes. Western blot analysis of (A) cleaved PARP and (B) cleaved caspase-3 after treatment of I+T conditioned medium in the presence of HA, PRP, and HA+PRP. *p<0.05, compared with the value in cells cultured in I+T using student t-test. The results are presented as mean ± S.D. for 15 independent experimental replicates.