Research Paper Volume 10, Issue 12 pp 4188—4196

Fluoxetine-mediated inhibition of endoplasmic reticulum stress is involved in the neuroprotective effects of Parkinson’s disease

Figure 4. Effects of FLX on ER stress in the brain of PD rats. (A) Transcriptional levels of Bip/GRP78, CHOP and caspase-3 were measured by RT-qPCR, n=6. (B-C) Translational levels of Bip/GRP78, p-XBP1, XBP1, CHOP and procaspase-3 were detected using Western blot, n=6 each group. *P<0.05, **P<0.01 versus control group; # P <0.05, ##P<0.01 versus rotenone-treated group.