Research Paper Volume 10, Issue 12 pp 4188—4196

Fluoxetine-mediated inhibition of endoplasmic reticulum stress is involved in the neuroprotective effects of Parkinson’s disease

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Figure 4. Effects of FLX on ER stress in the brain of PD rats. (A) Transcriptional levels of Bip/GRP78, CHOP and caspase-3 were measured by RT-qPCR, n=6. (B-C) Translational levels of Bip/GRP78, p-XBP1, XBP1, CHOP and procaspase-3 were detected using Western blot, n=6 each group. *P<0.05, **P<0.01 versus control group; # P <0.05, ##P<0.01 versus rotenone-treated group.