Research Paper Volume 10, Issue 12 pp 4213—4223

Caloric restriction is associated with preservation of muscle strength in experimental cancer cachexia

Figure 2. Daily food intake throughout the experiment. Grouped histograms depicting the mean daily food intake per group in C26 tumor-bearing (TB) male CD2F1 mice with ad libitum access to chow (dietary reference intake [DRI], n = 10); C26 TB mice on a 30% caloric restriction (CR, n = 10) diet; non-tumor bearing (NTB) mice with matched intake (MI, n= 10); NTB mice on a 30% caloric restriction (n = 10). The vertical bars indicate daily measurements of food intake, ranging from day 0 to 35, for each specified group. Food intake is expressed as grams (g). Food intake of C26 TB DRI mice decreased in the final days preceding sacrifice from 3.8 g to 2.9 g (p = 0.0002, paired-sample t-test). Consequently, food intake decreased in the other groups accordingly.