Research Paper Volume 11, Issue 18 pp 7339—7356

Leonurine ameliorates D-galactose-induced aging in mice through activation of the Nrf2 signalling pathway

Figure 4. Effect of leonurine on spatial learning and memory impairment in the MWM task. (A) Escape latencies of the training trial. (B) Escape latencies at the 5th day of the training trial. (C) Swimming time in the target quadrant during probe test. (D) The number of crossings into the former location of the platform during the probe test. (E) Swimming trajectory of each group of mice. All data are expressed as means ± SD (n = 12). #P < 0.05 and ##P < 0.01 vs control group; *P < 0.05 and **P < 0.01 vs model group.