Research Paper Volume 11, Issue 7 pp 2071—2081

Early-life vancomycin treatment promotes airway inflammation and impairs microbiome homeostasis

Figure 2. Vancomycin aggravates inflammatory cell infiltration and mucus secretion in the OVA-induced asthma model. (A, C) Representative H&E and PAS staining of lung sections. (B, D) Peribronchiolar and perivascular inflammation score, and mucus production with semi-quantification (score: 0–4) under the microscope (n = 8) (10 × 20 magnification). Data shown as means ± SEM. (*P < 0.05; **P < 0.01; ***P< 0.001; ****P< 0.0001).