Research Paper Volume 11, Issue 7 pp 2071—2081

Early-life vancomycin treatment promotes airway inflammation and impairs microbiome homeostasis

Figure 5. The representatively changed bacteria in the gut and lung followed by vancomycin administration in the OVA-induced asthma model. (A) Relative abundance of Family_XIII, Defluviitaleaceae, Alcaligenaceae and Desulfurellaceae. Different symbols represent the fecal samples from each group. (B, C) Changed species in the lung were classified into 3 groups. The representative bacteria were listed based on the relative abundance. Data were shown as means ± SEM, n = 3. (*P< 0.05. **P < 0.01; ***P < 0.001) (OVA.S: stool sample of the OVA group; VAN.OVA.S: stool sample of the Van-OVA group; OVA.L: lung tissue of the OVA group; VAN.OVA.L: lung tissue of the Van-OVA group).