Research Paper Volume 11, Issue 8 pp 2202—2216

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)

Figure 1. The combination of low-dose Doxycycline and Azithromycin inhibits mammosphere formation. Note that this combination in MCF7 breast cancer cells, inhibited 3D mammosphere formation with greater efficacy than the two drugs alone. *p < 0.05; ***p < 0.001; ****p < 0.0001. DOX, Doxycycline; AZI, Azithromycin.