Research Paper Volume 11, Issue 8 pp 2202—2216

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)

Figure 11. Direct side-by-side metabolic comparison of low-dose Vitamin C with the DAV triple combination: Seahorse profiles. Note that low-dose Vitamin C increases oxidative mitochondrial metabolism, while the DAV triple combination results in severe ATP depletion. Also, note that low-dose Vitamin C and the DAV triple combination both increase glycolysis.