Research Paper Volume 11, Issue 8 pp 2202—2216

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)

Figure 12. Direct side-by-side metabolic comparison of low-dose Vitamin C with the DAV triple combination: Bar graphs. Note that low-dose Vitamin C increases basal respiration, ATP production and maximal respiration, while the DAV triple combination decreases all three of these parameters. Also, note that low-dose Vitamin C and the DAV triple combination both increase glycolysis, while decreasing glycolytic reserve capacity. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.