Research Paper Volume 11, Issue 8 pp 2202—2216

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)

Figure 4. The Doxycycline-Azithromycin combination shifts MCF7 cancer cells from a highly energetic state to a metabolically quiescent state. We examined the metabolic profile of MCF7 cell monolayers pre-treated with the combination of Doxycycline (1 μM) and Azithromycin (1 μM) for 3 days, using the Seahorse XFe96 analyzer. *p < 0.05. DOX, Doxycycline; AZI, Azithromycin.