Research Paper Volume 11, Issue 8 pp 2202—2216

Doxycycline, Azithromycin and Vitamin C (DAV): A potent combination therapy for targeting mitochondria and eradicating cancer stem cells (CSCs)

Figure 6. MCF7 3D mammosphere formation is extremely sensitive to inhibition by combined treatment with Doxycycline [1 μM], Azithromycin [1 μM] and Vitamin C [250 μM] (D+A+VitC). Bar graphs are shown as the mean ± SD, t-test, two-tailed. Note that approximately 90% inhibition was observed with the triple combination. ****p < 0.0001.