Figure 4. Correlations between connectivity change and CF in the entire sample. In the cortical-striatal network, the partial correlation analysis showed CF change was significantly correlated with the anterior regions, including L SFG, R ACC, L MFG, LMFG2 and L MedFG. The CF change showed negative correlation trend with the posterior regions but not significant, including L PCC, R Cuneus and L OG. Note: L, left; R, right; SFG, superior frontal gyrus; ACC, anterior cingulate cortex; PCC, posterior cingulate cortex; MedFG, medial frontal gyrus, MFG, middle frontal gyrus; OG, occipital gyrus. p values here are FDR-corrected across all regions. CF, cognitive fatigue; IIVRT, intra-individual variability of reaction time.