Research Paper Volume 11, Issue 8 pp 2312—2326

Cognitive fatigue and cortical-striatal network in old age

Figure 5. Relationships between the anterior and posterior cortical-striatal network functional connectivity and CF. (A) During the cognitively fatiguing tasks, both of the anterior and posterior network showed significant interaction effects between subgroup (high- vs. low-CF) and block (1 vs. 6), that connectivity strength increased in low-CF group while decreased in high-CF group (B) Although CF was negatively associated with change of anterior or posterior connectivity, the negative relationship was more robust in anterior cortical-striatal network. Note: CF, cognitive fatigue; IIVRT, intra-individual variability of reaction time.