Research Paper Volume 11, Issue 8 pp 2457—2476
Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice
Figure 2. Behavioral evaluation of 5-month-old Tbk1-NKO mice. (A–B) Clasping and footprint assessment. (C–D) Stretch width and stride length measurements (n = 5). (E–G) Body weight, grip power, and rotarod latency (n = 13-21). (H–I) Morris water maze’s learning and memory test. Latency to reach the platform and number of target quadrant crosses (n = 13-21). *P < 0.05, compared to WT control.