Research Paper Volume 11, Issue 8 pp 2457—2476

Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice

Figure 2. Behavioral evaluation of 5-month-old Tbk1-NKO mice. (AB) Clasping and footprint assessment. (CD) Stretch width and stride length measurements (n = 5). (EG) Body weight, grip power, and rotarod latency (n = 13-21). (HI) Morris water maze’s learning and memory test. Latency to reach the platform and number of target quadrant crosses (n = 13-21). *P < 0.05, compared to WT control.