Research Paper Volume 11, Issue 8 pp 2457—2476

Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice

Figure 3. Behavioral evaluation of 14-month-old Tbk1-NKO mice. (AB) Latency to reach the platform and number of target quadrant crosses in the Morris water maze (n = 9-10). *P < 0.05, compared to WT control. (CD) Swimming distances and body weight (n = 9-10). *P < 0.05, compared to WT mice.