Research Paper Volume 11, Issue 8 pp 2457—2476

Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice

Figure 5. Identification of protein aggregates. Ubiquitin, p62, and TDP-43 immunostaining of the cortex (co) and cerebellum (cb) of Tbk1-NKO and WT mice (n = 3). Bar = 20 μm. Arrows indicate protein aggregates.