Research Paper Volume 11, Issue 11 pp 3785—3794

Metformin prevents murine ovarian aging

Figure 4. Effects of MET on oxidative damage markers and the p16 level in both groups. (A). The representative IHC images of p16 protein in the CON and MET mouse ovaries. (B). Average IOD of the markers in the two groups. Values are expressed as mean± S.E.M. *indicates a significant difference between the two group. *P<0.05, **P < 0.01.