Research Paper Volume 11, Issue 13 pp 4338—4353

Targeting HMGB1 by ethyl pyruvate ameliorates systemic lupus erythematosus and reverses the senescent phenotype of bone marrow-mesenchymal stem cells

Figure 1. (A) We collected bone marrow supernatant from normal people and SLE patients. Bone marrow supernatant samples were analyzed using a proteomics approach. (B) Elisa showed that HMGB1 expression levels were high in bone marrow supernatant and serum of SLE patients. (Bar represents mean ± SD,*P < 0.05 compared with the normal group) (NOR=normal group, SLE=systemic lupus erythematosus patients group).