Editorial Volume 11, Issue 13 pp 4300—4302

Statins: benefits and risks revisited

Figure 1. Statin benefits and adverse effects. Statin therapy shows cardioprotective and antiatherogenic effect, thereby reducing mortality. However, statins show also adverse effects, particularly on brown adipose tissue (BAT), liver and muscle function. We suggest that BAT dysfunction might be the mediator of statin induced insulin resistance and type 2 diabetes.