LncRNA <i>MIR22HG</i> abrogation inhibits proliferation and induces apoptosis in esophageal adenocarcinoma cells via activation of the STAT3/c-Myc/FAK signaling

Wenmei Su; Chunfang Guo; Lihui Wang; Zhuwen Wang; Xia Yang; Feiyu Niu; Daniel Tzou; Xiao Yang; Xiaobi Huang; Jiancong Wu; Xiaorao Chen; Lei Zou; Zhixiong Yang; Guoan Chen

doi:doi:10.18632/aging.102071

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Research Paper Volume 11, Issue 13 pp 4587—4596

LncRNA MIR22HG abrogation inhibits proliferation and induces apoptosis in esophageal adenocarcinoma cells via activation of the STAT3/c-Myc/FAK signaling

Figure 2. Knockdown of MIR22HG inhibits cancer cell migration and invasion. Migration (A) and invasion (B) were decreased after MIR22HG siRNA transfection in OE33 and FLO-1 cells. The bar chart shows the relative number of migration and invasion cells. Scale bar: 5mm. Values represented the mean ± s.d. from three independent experiments. *P < 0.05, **P < 0.01.