Research Paper Volume 11, Issue 13 pp 4587—4596

LncRNA MIR22HG abrogation inhibits proliferation and induces apoptosis in esophageal adenocarcinoma cells via activation of the STAT3/c-Myc/FAK signaling

Figure 5. Schematic the potential signaling affected by knockdown of MIR22HG.MIR22HG siRNA inhibits STAT3 proteins, then affects c-MYC and FAK proteins to modulate the cells proliferation, migration, invasion and induced apoptosis in esophagus cancer.