Figure 1. Verification of PD in mice treated with MPTP. (A–C) Effect of MPTP on motor function impairment by assess the time required to descend the pole in the vertical grid test (A), hanging duration in the horizontal grid test (B), and non-resting tremor using the Kaplan-Meier method and Log rank test (C). (D) Striatal 5-HT levels measured using HPLC. (E) Striatal DA levels measured using HPLC. (F) Representative photomicrographs of IHC staining for TH. (G) Statistical analysis of IHC staining for TH. In all panels, bars depict the mean±SD; *p<0.05.