Review Volume 11, Issue 13 pp 4757—4771

Circular RNAs in leukemia

Figure 4. CircRNAs and their correlation with miRNAs in AML. The figure summarizes the reported circRNAs that functioning in AML. The innermost circle described host genes (Blue rectangle) and the red ovals in the middle are circRNAs that transcribed from them. The outermost circle exhibited targeted miRNAs. Solid lines connect circRNAs and their target miRNAs (Green pentagon). Dashed lines are used to connect miRNAs (Grey box) that have not been validated experimentally or proposed to interact with circRNAs in other diseases.