Research Paper Volume 11, Issue 13 pp 4463—4477

Let-7f-5p suppresses Th17 differentiation via targeting STAT3 in multiple sclerosis

Figure 1. MiRNA expression profiling of peripheral blood CD4+ T cells from MS patients and healthy controls. (A) The lengths of small RNAs from the two pooled samples from the multiple sclerosis (MS) patients and healthy controls (HC). (B) Significant alterations were observed between the miRNA expression profiles of the MS patients and healthy controls. (C) Heat map of the significantly altered miRNAs (sequencing reads > 200 and fold-change > 2) obtained from Illumina high-throughput sequencing.