Figure 5. LncRNA MEG3 was correlated to IGF1 via MiR-27a-3p. (A) IGF1 expression in periodontitis periodontal tissues compared with healthy periodontal tissues. (B) Expression of IGF1 in 0h, 24h, 7d, 14d and 21d after osteogenic induction. (C) MiR-27a-3p directly targeted IGF1. (D–F) Expression of MEG3, miR-27a-3p and IGF1 in PDLSCs of each group. ** P < 0.01, compared with the NC group.