Research Paper Volume 11, Issue 15 pp 5351—5367

Long intergenic non-protein coding RNA 511 promotes the progression of osteosarcoma cells through sponging microRNA 618 to upregulate the expression of maelstrom

Figure 1. LncRNA microarray analysis and high expression of LINC00511 in OS. (A) Heatmap of lncRNA expression in OS tissues (n=6). LncRNAs were selected based on Flod change value>2 and P<0.05; the overexpressed lncRNAs are shown in red, and the downregulated lncRNAs are shown in green. (B) The expression of LINC00511 in Tumor tissues was higher than that in adjacent tissues as detected by qRT-PCR. **P<0.01 compared to the Adjacent group. (C) The expression of LINC00511 in OS cell lines, including MG-63, HOS, Saos-2 and 143B. *P<0.05 and **P<0.01 compared to the noncancerous osteoblast cell line hFOB 1.19.