Research Paper Volume 11, Issue 15 pp 5518—5534

Frailty in middle age is associated with frailty status and race-specific changes to the transcriptome

Figure 4. Frailty-associated biological pathways in whites. Differentially expressed genes between non-frail and frail whites were imputed into Parametric Analysis of Gene Set Enrichment (PAGE) analysis. Significantly changed gene sets, associated with biological processes, organized by Z-score, are shown here. GO terms associated with inflammation and immune response are highlighted in red.