Research Paper Volume 11, Issue 15 pp 5548—5569

Ginseng increases Klotho expression by FoxO3-mediated manganese superoxide dismutase in a mouse model of tacrolimus-induced renal injury

Figure 3. Effect of KRGP administration on Tac-induced mitochondrial ultrastructure in a mouse model. (A) Representative transmission electron micrographs of mitochondrial ultrastructure in the proximal tubules. Asterisks indicate mitochondria. (B and C) Quantitative analysis of number and size of mitochondria. BB, brush border. N, Nucleus. Bar = 1 μm. Data are presented as mean ± SE. n = 8. #P < 0.05.