Expression of Concern
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 11, Issue 15 pp 5744—5756
miR-627-3p inhibits osteosarcoma cell proliferation and metastasis by targeting PTN
Figure 6. MiR-627-3p inhibits invasion by HOS cells in vivo. (A, B) Livers were dissected from mice and either macroscopically photographed or sectioned and stained with hematoxylin-eosin. (C) Statistical results for the number of metastases. ** P< 0.05. (D, E) Western blot and real-time PCR analyses showing the Effects of miR-627-3p agomir on expression of PTN, Cyclin D1 and MMP2 in tumor tissues dissected from livers. Data are the mean ± SEM. ** P< 0.05. (F) Schematic diagram of the regulation of PTN by miR-627-3p and its effects on osteosarcoma cell proliferation and metastasis.