The senescence-associated secretory phenotype (SASP) from mesenchymal stromal cells impairs growth of immortalized prostate cells but has no effect on metastatic prostatic cancer cells

Nicola Alessio; Domenico Aprile; Tiziana Squillaro; Giovanni Di Bernardo; Mauro Finicelli; Mariarosa AB Melone; Gianfranco Peluso; Umberto Galderisi

doi:doi:10.18632/aging.102172

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Research Paper Volume 11, Issue 15 pp 5817—5828

The senescence-associated secretory phenotype (SASP) from mesenchymal stromal cells impairs growth of immortalized prostate cells but has no effect on metastatic prostatic cancer cells

Figure 3. Comparison of SASP contents. Venn diagram showing common and specific proteins among secretomes obtained from X-ray-irradiated or H₂0₂-treated or senescent-replicative MSCs.