Research Paper Volume 11, Issue 17 pp 6734—6761

MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer

Figure 8. Effects of GRIA3 overexpression on NSCLC cell viability, migration and invasion in vitro. (A) GRIA3 protein expression by western blotting after transfection with GRIA3 or vector. (B) Representative images of the MTT assay of A549 and HCC827 cells transfected with GRIA3 or vector. (C) Representative images of the wound healing assay of A549 and HCC827 cells transfected with GRIA3 or vector. (D, E) Representative images (upper) and quantification (lower) of the Transwell migration assay (D) and Transwell invasion assay (E) of A549 and HCC827 cells transfected with GRIA3 or vector. Values are mean ± SD, *P < 0.05, **P < 0.01, one-way ANOVA.