Research Paper Volume 11, Issue 17 pp 6930—6940

An eight-long non-coding RNA signature as a candidate prognostic biomarker for bladder cancer

Figure 2. Gene enrichment analysis of the lncRNA-signature. (A) WGCNA method were performed to cluster genes that highly correlated with the risk scores. Clustering dendrogram and eigengene adjacency heatmap were generated using genes associated with the eight-lncRNA signature. (B) The pathways related with eight-lncRNA signature were clustered using Metascape. The cluster was made up of the best enriched pathways. The top 20 enriched pathways were shown (right panel) and the top 2 enriched pathways were marked (left panel). (C) The histogram of the top 20 enriched pathways associated with risk score was arranged by -Log10P value. Each bar represented one enriched term and was colored by -Log10P value.