Research Paper Volume 11, Issue 18 pp 7386—7401

lncRNA DLEU2 modulates cell proliferation and invasion of non-small cell lung cancer by regulating miR-30c-5p/SOX9 axis

Figure 5. Effect of lncRNA/miR-30c-5p/SOX9 axis on cell proliferation, invasion, migration, and apoptosis. (AB) Cell viability was determined by CCK-8 assay; (C, G, K, O) The colony formatting assay was used to evaluate the proliferation activity of A549 and LLC cells; (D, H, L, P) The invasive ability of A549 and LLC cells were detected by Transwell assay; (E, I, M, Q) The migration abilities of tumor cells were assessed by wound healing assay; (F, J, N, R) Flow cytometric analysis of apoptosis in A549 and LLC cells; *p<0.05, **p<0.01, ***p<0.001, compared with control group.