Research Paper Volume 11, Issue 17 pp 7021—7035

Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging

Figure 5. NRF2 protected against oxidative stress in EPCs during aging. ROS levels were detected by fluorescence imaging (green, 100×) (A, E) and flow cytometry (B, F) in different groups of EPCs. The levels of SOD (C, G) and malondialdehyde (D, H) were also assessed in the supernatants of EPCs. *P<0.05. Y, young; MA, middle-aged; A, aged. A+tBHQ, aged EPCs treated with tBHQ.