Research Paper Volume 11, Issue 17 pp 7021—7035

Reduced NRF2 expression suppresses endothelial progenitor cell function and induces senescence during aging

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Figure 5. NRF2 protected against oxidative stress in EPCs during aging. ROS levels were detected by fluorescence imaging (green, 100×) (A, E) and flow cytometry (B, F) in different groups of EPCs. The levels of SOD (C, G) and malondialdehyde (D, H) were also assessed in the supernatants of EPCs. *P<0.05. Y, young; MA, middle-aged; A, aged. A+tBHQ, aged EPCs treated with tBHQ.