Research Paper Volume 11, Issue 17 pp 7036—7050

Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells

class="figure-viewer-img"

Figure 2. Curcumin enhanced the expression of autophagy-related genes encoding proteins, Beclin1, Atg5, and Atg16L1 in N2a/APP695swe cells. (AF) Western blot analysis of Beclin1, Atg5, Atg16α and Atg16β in each group; Representative blot (AB) and summary graph of densitometric analysis (CF); The data represent as mean ± SEM of a typical series of 3 experiments (# P<0.05, compared to the WT group; * P<0.01, compared to the APP or DMSO group).