Research Paper Volume 11, Issue 17 pp 7150—7168

Conclusions from a behavioral aging study on male and female F2 hybrid mice on age-related behavior, buoyancy in water-based tests, and an ethical method to assess lifespan

Figure 2. Physiological parameters of mice in the cohorts for behavioral assessment. (A) There was no difference in body weight between the cohorts, but (B) DEXA analysis showed that (pM7-F7=0.0078, pM15-F15=0.0011; and lean mass increased with age in males pM7-22=0.040, pM15-22=0.036; Mann Whitney), whereas (C) females exhibited increased fat mass as compared to males (pM7-F7=0.0023, pM15-F15=0.0012; Welch’s t-test). Values are mean ± SEM; nM=7, nM15=10, nM22=10, nF7=9, nF15=12, nF22=7.