Research Paper Volume 11, Issue 17 pp 7150—7168

Conclusions from a behavioral aging study on male and female F2 hybrid mice on age-related behavior, buoyancy in water-based tests, and an ethical method to assess lifespan

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Figure 2. Physiological parameters of mice in the cohorts for behavioral assessment. (A) There was no difference in body weight between the cohorts, but (B) DEXA analysis showed that (pM7-F7=0.0078, pM15-F15=0.0011; and lean mass increased with age in males pM7-22=0.040, pM15-22=0.036; Mann Whitney), whereas (C) females exhibited increased fat mass as compared to males (pM7-F7=0.0023, pM15-F15=0.0012; Welch’s t-test). Values are mean ± SEM; nM=7, nM15=10, nM22=10, nF7=9, nF15=12, nF22=7.