Research Paper Volume 11, Issue 17 pp 7187—7196

STAT3 inhibitor sensitized KRAS-mutant lung cancers to RAF inhibitor by activating MEK/ERK signaling pathway

Figure 5. Combined AZ628 and BP-1-102 inhibited tumor growth in vivo. (A) Photographs of the xenograft KRAS(G12V) H441 tumors treated with single or combination drugs. (B) Tumor volume was measured. (C) Tumor weight was measured. *p<0.05. ***p<0.001.