Research Paper Volume 11, Issue 18 pp 7442—7456

Analyses of an epigenetic switch involved in the activation of pioneer factor FOXA1 leading to the prognostic value of estrogen receptor and FOXA1 co-expression in breast cancer

Figure 10. Relationship of FOXA1 expression and prognosis in breast cancers. Recurrence-free survival (RFS) curves calculated by Kaplan-Meier plotter for tumor patients with ER + (A) and ER- (B), respectively. Survival probability is displayed on the y-axis, time (in months) on the x-axis. Black curves represent low FOXA1 expression, and red curves represent high FOXA1 expression. It can be noted that enhanced expression of FOXA1 leads to differences in RFS only in the ER + background (Panel A).